TOXICITY ASSESSMENT OF MESOPOROUS SILICA NANOPARTICLES UPON INTRAVENOUS INJECTION IN MICE: IMPLICATIONS FOR DRUG DELIVERY

Toxicity Assessment of Mesoporous Silica Nanoparticles upon Intravenous Injection in Mice: Implications for Drug Delivery

Nanoparticles are popular tools utilized to selectively deliver drugs and contrast agents for identification and treatment of disease.To determine the usefulness and translational potential of mesoporous silica nanoparticles (MSNs), further evaluations of toxicity are required.MSNs are among the most utilized nano-delivery systems due to ease of sy

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Fatigue Assessment of Existing Bridge Members

Correct consideration of the service load effects plays a very important role on assessment of railway bridges, especially on fatigue assessment.Eurocode EN 1991-2 introduces twelve types of service trains and prescribes their sequel in normal transpharm online shopping and heavy duty.The service trains, consisting of locomotive and defined number

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Global Spread of Mutant PfCRT and Its Pleiotropic Impact on Plasmodium falciparum Multidrug Resistance and Fitness

ABSTRACT The global spread of Plasmodium falciparum chloroquine resistance transporter (PfCRT) variant haplotypes earlier caused the widespread loss of chloroquine (CQ) efficacy.In Asia, novel PfCRT mutations that emerged on the Dd2 allelic background have recently been implicated in high-level resistance to piperaquine, and N326S and I356T have be

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